[GenABEL-dev] Journal Club on Statistical Genomics

[L.C. Karssen]

On Fri, 2011-04-01 at 19:17 +0200, Yurii Aulchenko wrote:
> Ok, I see your point. I would suggest we take an 'evolutionary'
> approach.
I agree.

>  Let me elaborate a bit on that.
> 

> I would think the same may work for the methodology forum. At first,
> introduce single forum, and then see how it goes. I actually can
> imagine that we may be willing to move few topics (or posts) from
> GenABEL-user to the methodology discussion :)
Indeed. I think this is the way to go to.


Lennart.


> 
> best wishes,
> Yurii
> 
> On Fri, Apr 1, 2011 at 11:04 AM, Maria G <mgmaria at yandex.ru> wrote:
> > Hi dear all :)
> >
> >> Would you have a clear-cut question of type (3)
> >
> >
> > In the section - Methodological nuances: «How to… ?» - I would discuss mostly questions of "how does the method work and why in a specific situations this one is better than the other".
> >
> > A good actual example we have right now on our GenABEL forum:
> >
> > http://forum.genabel.org/viewtopic.php?f=6&t=217&p=587#p587
> >
> > where the question has arisen:
> >
> > "If there are different methods of obtaining p-values from linear regression for association analysis and which one should is better to use?"
> >
> > And it's obvious that, might be, we just need a little bit more theoretical information to answer it and to find the differences between Plink and R-based GeanABEL (which is confusing for a lot of people! ;) ..)
> >
> > My personal feeling as a user of GenABEL is, that I want to understand exactly what's going on with my data, but not just to push the correct buttons in such a nice and powerfull tool  ;)
> >
> > My best wishes to all of yours :)
> >
> > Mascha
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-- 
-----------------------------------------------
L.C. Karssen
Erasmus MC
Department of Epidemiology
Room Ee 2224

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phone: +31-10-7044217
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e-mail: l.karssen at erasmusmc.nl
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