[GenABEL-dev] Journal Club on Statistical Genomics

Maria G mgmaria at yandex.ru
Mon Apr 4 09:54:45 CEST 2011


Sounds good! Let's see what will happend :) 

01.04.2011, 23:51, "L.C. Karssen" <l.karssen at erasmusmc.nl>:
> On Fri, 2011-04-01 at 19:17 +0200, Yurii Aulchenko wrote:
>
>>  Ok, I see your point. I would suggest we take an 'evolutionary'
>>  approach.
>
> I agree.
>
>>   Let me elaborate a bit on that.
>>  I would think the same may work for the methodology forum. At first,
>>  introduce single forum, and then see how it goes. I actually can
>>  imagine that we may be willing to move few topics (or posts) from
>>  GenABEL-user to the methodology discussion :)
>
> Indeed. I think this is the way to go to.
>
> Lennart.
>
>>  best wishes,
>>  Yurii
>>
>>  On Fri, Apr 1, 2011 at 11:04 AM, Maria G <mgmaria at yandex.ru>; wrote:
>>>  Hi dear all :)
>>>>  Would you have a clear-cut question of type (3)
>>>  In the section - Methodological nuances: «How to… ?» - I would discuss mostly questions of "how does the method work and why in a specific situations this one is better than the other".
>>>
>>>  A good actual example we have right now on our GenABEL forum:
>>>
>>>  http://forum.genabel.org/viewtopic.php?f=6&t=217&p=587#p587
>>>
>>>  where the question has arisen:
>>>
>>>  "If there are different methods of obtaining p-values from linear regression for association analysis and which one should is better to use?"
>>>
>>>  And it's obvious that, might be, we just need a little bit more theoretical information to answer it and to find the differences between Plink and R-based GeanABEL (which is confusing for a lot of people! ;) ..)
>>>
>>>  My personal feeling as a user of GenABEL is, that I want to understand exactly what's going on with my data, but not just to push the correct buttons in such a nice and powerfull tool  ;)
>>>
>>>  My best wishes to all of yours :)
>>>
>>>  Mascha
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