[Mediation-information] Interaction between exposures?

[Mashhood Sheikh]

Dear Dustin and Kosuke,

 

Is it
possible to estimate the direct and indirect effects when there is an
interaction between exposures (X1, X2), regressed on outcome Y? Since X2 is
also a mediator-outcome confounder between the mediation model X1>M>Y, and
X1 is also a mediator-outcome confounder between the mediation model
X2>M>Y, it is important to include them in the model as covariates, but
than what about the interaction between them? Note: all variables, X1, X2, M,
and Y are binary.


I would highly appreciate any tips...



Thankfully,

Mashhood

Institute
of Community Medicine,

University
of Tromsø,

Norway. 		 	   		  
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