[Seqinr-commits] r2058 - pkg/man
noreply at r-forge.r-project.org
noreply at r-forge.r-project.org
Tue Jul 4 18:10:09 CEST 2017
Author: jeanlobry
Date: 2017-07-04 18:10:09 +0200 (Tue, 04 Jul 2017)
New Revision: 2058
Modified:
pkg/man/kaks.Rd
Log:
Adding the original reference for Ka and Ks computation, that is Li et al. 1985
Modified: pkg/man/kaks.Rd
===================================================================
--- pkg/man/kaks.Rd 2017-07-04 13:07:40 UTC (rev 2057)
+++ pkg/man/kaks.Rd 2017-07-04 16:10:09 UTC (rev 2058)
@@ -8,7 +8,7 @@
}
\arguments{
\item{x}{ An object of class \code{alignment}, obtained for instance by importing into R the data from an alignment file with the \code{\link{read.alignment}} function. This is typically a set of coding sequences aligned at the protein level, see \code{\link{reverse.align}}.}
- \item{verbose}{ If TRUE add to the results the value of L0, L2, L4 (respectively the number of non-synonymous sites, of 2-fold synonymous sites, of 4-fold synonymous sites), A0, A2, A4 (respectively the number of transitional changes at non-synonymous, 2-fold, and 4-fold synonymous sites ) and B0, B2, B4 (respectively the number of transversional changes at non-synonymous, 2-fold, and 4-fold synonymous sites).}
+ \item{verbose}{ If TRUE add to the results the value of L0, L2, L4 (respectively the frequency of non-synonymous sites, of 2-fold synonymous sites, of 4-fold synonymous sites), A0, A2, A4 (respectively the number of transitional changes at non-synonymous, 2-fold, and 4-fold synonymous sites ) and B0, B2, B4 (respectively the number of transversional changes at non-synonymous, 2-fold, and 4-fold synonymous sites).}
\item{debug}{ If TRUE turns debug mode on.}
\item{forceUpperCase}{ If TRUE, the default value, all character in sequences are forced to the upper case
if at least one 'a', 'c', 'g', or 't' is found in the sequences.
@@ -22,6 +22,8 @@
\item{ vka }{ variance matrix of Ka }
}
\references{
+Li, W.-H., Wu, C.-I., Luo, C.-C. (1985) A new method for estimating synonymous and nonsynonymous rates of nucleotide substitution considering the relative likelihood of nucleotide and codon changes. \emph{Mol. Biol. Evol}, \bold{2}:150-174\cr
+
Li, W.-H. (1993) Unbiased estimation of the rates of synonymous and nonsynonymous substitution.
\emph{J. Mol. Evol.}, \bold{36}:96-99.\cr
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