[Seqinr-commits] r1902 - pkg/man
noreply at r-forge.r-project.org
noreply at r-forge.r-project.org
Thu Jun 2 16:27:43 CEST 2016
Author: jeanlobry
Date: 2016-06-02 16:27:43 +0200 (Thu, 02 Jun 2016)
New Revision: 1902
Modified:
pkg/man/zscore.Rd
Log:
documentation bug fix and UTF-8
Modified: pkg/man/zscore.Rd
===================================================================
--- pkg/man/zscore.Rd 2016-06-02 14:11:38 UTC (rev 1901)
+++ pkg/man/zscore.Rd 2016-06-02 14:27:43 UTC (rev 1902)
@@ -3,7 +3,7 @@
\alias{zscore}
\title{Statistical over- and under- representation of dinucleotides in a
sequence}
-\encoding{latin1}
+\encoding{UTF-8}
\description{
These two functions compute two different types of statistics for the
measure of statistical dinculeotide over- and under-representation :
@@ -34,9 +34,12 @@
nucleotide \emph{x} and nucleotide \emph{y}. It is equal to 1.00 when
dinucleotide \emph{xy} is formed by pure chance, and it is superior
(respectively inferior) to 1.00 when dinucleotide \emph{xy} is over-
- (respectively under-) represented.
+ (respectively under-) represented. Note that if you want to reproduce
+ Karlin's results you have to compute the statistic from the sequence
+ concatenated with its inverted complement that is with something
+ like \code{rho(c(myseq, rev(comp(mysed))))}.
- The \code{zscore} statistic, as presented in Palmeira, L., Guéguen, L.
+ The \code{zscore} statistic, as presented in Palmeira, L., Guéguen, L.
and Lobry JR. (2006). The statistic is the normalization of the
\code{rho} statistic by its expectation and variance according to a
given random sequence generation model, and follows the
@@ -49,7 +52,7 @@
The \code{base} model allows for random sequence generation by
shuffling (with/without replacement) of all bases in the sequence.
Analytical computations are available for this model: either as an
- approximation for large sequences (cf. Palmeira, L., Guéguen, L.
+ approximation for large sequences (cf. Palmeira, L., Guéguen, L.
and Lobry JR. (2006)), either as the exact analytical formulae
(cf. Schbath, S. (1995)).
@@ -76,12 +79,12 @@
Karlin S. and Cardon LR. (1994) Computational DNA sequence analysis.
\emph{Annu Rev Microbiol}, \bold{48}:619-654.
- Schbath, S. (1995) Étude asymptotique du nombre d'occurrences d'un
- mot dans une chaîne de Markov et application à la recherche de mots
- de fréquence exceptionnelle dans les séquences d'ADN.
- \emph{Thèse de l'Université René Descartes, Paris V}
+ Schbath, S. (1995) Ãtude asymptotique du nombre d'occurrences d'un
+ mot dans une chaîne de Markov et application à la recherche de mots
+ de fréquence exceptionnelle dans les séquences d'ADN.
+ \emph{Thèse de l'Université René Descartes, Paris V}
- Palmeira, L., Guéguen, L. and Lobry, J.R. (2006) UV-targeted dinucleotides
+ Palmeira, L., Guéguen, L. and Lobry, J.R. (2006) UV-targeted dinucleotides
are not depleted in light-exposed Prokaryotic genomes.
\emph{Molecular Biology and Evolution},
\bold{23}:2214-2219.
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