[Patchwork-commits] r167 - www
noreply at r-forge.r-project.org
noreply at r-forge.r-project.org
Wed Apr 10 15:49:55 CEST 2013
Author: sebastian_d
Date: 2013-04-10 15:49:55 +0200 (Wed, 10 Apr 2013)
New Revision: 167
Modified:
www/cg_resu.php
www/intro.php
Log:
add publikation info to homepage
Modified: www/cg_resu.php
===================================================================
--- www/cg_resu.php 2013-03-19 10:43:37 UTC (rev 166)
+++ www/cg_resu.php 2013-04-10 13:49:55 UTC (rev 167)
@@ -10,7 +10,8 @@
The clusters in the plot display regions of certain allelic constitution and copy number.
The copy number increases along the Coverage axis while paternal/maternal allele ratio
-becomes less balanced along the Allelic Imbalance axis.<br /><br />
+becomes less balanced along the Allelic Imbalance axis. We can use this information to determine the clusters probable copy number
+and allele content.<br /><br />
The chromosome in question is colored against a background of the complete genome in grey.
A colored circles gradient and size correlate with its segments position and size on the
@@ -18,15 +19,11 @@
The circles are semi-transparent so a darker hue, both for colored and grey,
indicate greater amount of genomic content in that region.<br /><br />
-We know that each cluster has a certain copy number and allele content and we know that
-a human is usually diploid (copy number 2, heterozygous). Finally we know that the average
+We know that each cluster has a certain copy number and allele content and we know that the average
copy number of the genome in question is at position 1 on the Coverage axis.
-We can use this information to determine the clusters probable copy number
-and allele content.<br /><br />
-
The far left cluster is the deletions, copy number 1. After copy number 1 we
-see two clusters, albeit the lower one does not have much content. This is pretty
-close to Coverage of 1 and as such they are most likely the two allelic states of copy number 2.
+see two clusters, albeit the lower one does not have much content. They are most likely
+the two allelic states of copy number 2.
Continuing with this reasoning the next set of clusters is copy number 3, etc.
This arrangement of the genome is easier to see from one of the plots generated by
Modified: www/intro.php
===================================================================
--- www/intro.php 2013-03-19 10:43:37 UTC (rev 166)
+++ www/intro.php 2013-04-10 13:49:55 UTC (rev 167)
@@ -19,7 +19,7 @@
If you have any feedback or questions please do not hesitate to contact us!
-<br /><br />
+<br /><br /><br /><br /><br />
<div style="text-align:center;">
<a href="http://www.medsci.uu.se" accesskey="1" tabindex="2">
@@ -27,14 +27,16 @@
src="http://www.medsci.uu.se/digitalAssets/22/22975_UU_logga_transp.png"
alt="Medical Sciences" title="Medical Sciences Uppsala University"></a>
</div>
+<br /><br /><br />
-<!--
<div style="text-align:center;">
<h4>Publication</h4>
-M Mayrhofer,S DiLorenzo,A Isaksson <br />
-Är detta en bra plats att ha publikationen? <br />
-Aftonbladet,25,DOI:23442342
+<a href="http://genomebiology.com/2013/14/3/R24/abstract" style="text-decoration:none;">
+Patchwork: allele-specific copy number analysis of whole genome sequenced tumor tissue</a> <br />
+Markus Mayrhofer, Sebastian DiLorenzo and Anders Isaksson <br />
+Genome Biology 2013, 14:R24 doi:10.1186/gb-2013-14-3-r24 <br />
+Published: 25 March 2013
</div>
--->
+
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