[GenABEL-dev] Review needed for MultiABEL

Xia Shen shenxia911 at gmail.com
Thu Oct 30 23:12:51 CET 2014


Dear list,

Thanks Lennart for a fairly good introduction of me! Following this, I would like to inform you that a new package, MultiABEL, has been committed to R-Forge and successfully built. This is the first (R-only) version, which performs multivariate GWA analysis, i.e. testing a group of (co)related phenotypes against each single variant. There are also a replication analysis module and a simple meta-analysis module included. The GWA module is compatible with both GenABEL (directly typed data) and DatABEL (imputed data) formats of genotypes.

I would kindly ask whether any of you could do a technical review of this new package, to ensure the coding follows GenABEL standards. You are certainly also welcome to contribute to future development of this package.

Thanks in advance!

Xia

Xia Shen, PhD
shen.se <http://shen.se/>

Department of Medical Epidemiology & Biostatistics
Karolinska Institutet
Nobels väg 12A
SE-171 77 Stockholm
SWEDEN

MRC Human Genetics Unit
MRC Institute of Genetics & Molecular Medicine
University of Edinburgh
Western General Hospital
Crewe Road
EH4 2XU Edinburgh
UK

> 
> Date: Thu, 30 Oct 2014 13:34:25 +0100
> From: "L.C. Karssen" <lennart at karssen.org>
> To: GenABEL Development list
> 	<genabel-devel at lists.r-forge.r-project.org>
> Subject: [GenABEL-dev] Introducing Xia Shen
> Message-ID: <54523051.4060502 at karssen.org>
> Content-Type: text/plain; charset="utf-8"
> 
> Dear list,
> 
> With this e-mail I'd like to introduce Xia Shen as a "new" member of our
> community. Some of you may know Xia from his contributions to the devel
> list or his work on GenABEL's polygenic_hglm.
> 
> In the past, both Yurii and I have worked with Xia in the past and now
> Xia has asked whether he could join the GenABEL project as well. Xia has
> a background in statistical genetics and has already worked on several R
> packages, notably bigRR [1] and hglm [2], which are both in the Suggests
> list of the GenABEL package.
> 
> Xia has been working on a new package he'd like to include in the
> GenABEL suite. I'm sure you will here more on that in the near future.
> In order to set up the package Xia has been given commit access to the
> SVN repo.
> 
> Xia, I wish you a warm welcome and look forward to your contributions.
> 
> Best,
> 
> Lennart.
> 
> 
> [1] http://cran.r-project.org/web/packages/bigRR/index.html
> [2] http://cran.r-project.org/web/packages/hglm/index.html
> -- 
> *-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*
> L.C. Karssen
> Utrecht
> The Netherlands
> 
> lennart at karssen.org
> http://blog.karssen.org
> GPG key ID: A88F554A
> -*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-*-

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