[GenABEL-dev] Question about probABLE

Erin C. Dunn erindunn at pngu.mgh.harvard.edu
Wed May 14 01:20:15 CEST 2014


Good Afternoon,

I am interested in possibly using probABLE for some genome-wide GxE analyses I am planning to run.  I was wondering if you could tell me whether probABLE would allow me to: (1) run Pete Kraft's d2f joint test (for the main genetic effect and test for GxE); (2) use dosage data; (3) have a continuous outcome; (4) and obtain robust SE.

It looks like probABLE would enable me to do all of these things.  I was hoping to have some verification of this before I embark down this path, as I haven't used this software before and would imagine the learning curve would be somewhat steep.

Any insights you might be able to share would be immensely helpful.

Thanks,
Erin

____________________________
Erin C. Dunn, ScD, MPH
Post-Doctoral Research Fellow
Psychiatric and Neurodevelopmental Genetics Unit
Center for Human Genetic Research
Massachusetts General Hospital
185 Cambridge Street
Simches, Room 6.252
Boston, MA 02114
erindunn at pngu.mgh.harvard.edu
617-726-9387 (work phone)
617-726-0830 (work fax)

To schedule a meeting, please visit my doodle poll:  http://doodle.com/erindunn



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