[GenABEL-dev] Question about probABLE
Erin C. Dunn
erindunn at pngu.mgh.harvard.edu
Wed May 14 01:20:15 CEST 2014
Good Afternoon,
I am interested in possibly using probABLE for some genome-wide GxE analyses I am planning to run. I was wondering if you could tell me whether probABLE would allow me to: (1) run Pete Kraft's d2f joint test (for the main genetic effect and test for GxE); (2) use dosage data; (3) have a continuous outcome; (4) and obtain robust SE.
It looks like probABLE would enable me to do all of these things. I was hoping to have some verification of this before I embark down this path, as I haven't used this software before and would imagine the learning curve would be somewhat steep.
Any insights you might be able to share would be immensely helpful.
Thanks,
Erin
____________________________
Erin C. Dunn, ScD, MPH
Post-Doctoral Research Fellow
Psychiatric and Neurodevelopmental Genetics Unit
Center for Human Genetic Research
Massachusetts General Hospital
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erindunn at pngu.mgh.harvard.edu
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