[Genabel-commits] r2007 - pkg/ProbABEL/doc
noreply at r-forge.r-project.org
noreply at r-forge.r-project.org
Wed Jul 22 17:34:00 CEST 2015
Author: lckarssen
Date: 2015-07-22 17:33:59 +0200 (Wed, 22 Jul 2015)
New Revision: 2007
Modified:
pkg/ProbABEL/doc/ProbABEL_manual.tex
Log:
Summary: ProbABEL documentation: Added a few lines of the exact models that are used when calculating the chi2_SNP column in case the --interaction option is used.
Based on this forum post: http://forum.genabel.org/viewtopic.php?f=10&t=945&p=2100#p2100
Modified: pkg/ProbABEL/doc/ProbABEL_manual.tex
===================================================================
--- pkg/ProbABEL/doc/ProbABEL_manual.tex 2015-07-09 17:13:02 UTC (rev 2006)
+++ pkg/ProbABEL/doc/ProbABEL_manual.tex 2015-07-22 15:33:59 UTC (rev 2007)
@@ -1,4 +1,4 @@
-\documentclass[12pt,a4paper]{article}
+\documentclass[12pt,a4paper]{scrartcl}
\title{Manual for ProbABEL v0.4.5}
\author{\emph{Current Programmers:} Lennart Karssen$^{1,2}$, Maarten
@@ -18,6 +18,14 @@
\usepackage[T1]{fontenc}
\usepackage{textcomp}
+% Use the Palatino font. The KOMA scrartcl document class uses a
+% sans-serif font for several labels/headinges. So we set those to
+% Palatino as well.
+\usepackage[osf,sc]{mathpazo}
+\linespread{1.05} % Palatino needs more leading (space between lines)
+\addtokomafont{descriptionlabel}{\normalfont\bfseries}
+\addtokomafont{sectioning}{\normalfont\bfseries}
+
\usepackage[svgnames]{xcolor}
\definecolor{webgreen}{rgb}{0,.5,0}
@@ -562,6 +570,12 @@
\textrm{trait} \sim \textrm{sex} + \textrm{age} + \textrm{SNP} +
\textrm{age} \times \mathrm{SNP}.
\end{equation*}
+In this case, the \texttt{chi2_SNP} column in the output file contains
+the $\chi_2^2$ statistic taken from the Likelihood ratio test. This
+LRT statistic is calculated based on a full model that contains all
+terms (sex, age, SNP and age$\times$SNP). The null model does not
+contain the terms that include the SNP.
+
The option \lstinline{--robust} allows you to compute so-called
``robust'' (a.k.a.~``sandwich'', a.k.a.~Hubert-White) standard errors
(cf.~section \ref{sec:methodology} ``Methodology'' for details).
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