[Genabel-commits] r668 - in pkg/GenABEL: . R man
noreply at r-forge.r-project.org
noreply at r-forge.r-project.org
Sun Mar 6 20:12:16 CET 2011
Author: yurii
Date: 2011-03-06 20:12:16 +0100 (Sun, 06 Mar 2011)
New Revision: 668
Modified:
pkg/GenABEL/CHANGES.LOG
pkg/GenABEL/DESCRIPTION
pkg/GenABEL/R/polygenic_hglm.R
pkg/GenABEL/man/convert.snp.illumina.Rd
pkg/GenABEL/man/convert.snp.mach.Rd
Log:
clean-up documentation + some cosmetics
Modified: pkg/GenABEL/CHANGES.LOG
===================================================================
--- pkg/GenABEL/CHANGES.LOG 2011-03-06 19:11:17 UTC (rev 667)
+++ pkg/GenABEL/CHANGES.LOG 2011-03-06 19:12:16 UTC (rev 668)
@@ -1,5 +1,11 @@
-*** v. 1.6-6 (2011.02.25)
+*** v. 1.6-6 (2011.03.06)
+Changes convert.snp.mach documentation to reflect the fact that
+the map-file should have header; changes to convert.snp.illumina
+documentation to reflect the nature of the data better; added
+option 'mapHasHeaderLine' to convert.snp.ped and updated documentation
+(resolving feature request #1317).
+
With suggestion and guidance from Xia Shen, added procedure 'polygenic_hglm'.
At the moment very experimental, and needs to pass checks before can be released.
Modified: pkg/GenABEL/DESCRIPTION
===================================================================
--- pkg/GenABEL/DESCRIPTION 2011-03-06 19:11:17 UTC (rev 667)
+++ pkg/GenABEL/DESCRIPTION 2011-03-06 19:12:16 UTC (rev 668)
@@ -6,7 +6,7 @@
Author: Yurii Aulchenko et al.
Maintainer: Yurii Aulchenko <i.aoultchenko at erasmusmc.nl>
Depends: R (>= 2.10.0), methods, MASS
-Suggests: qvalue, genetics, haplo.stats, DatABEL (>= 0.9-0), hglm
+Suggests: qvalue, genetics, haplo.stats, DatABEL (>= 0.9-0), hglm, MetABEL, ParallABEL, PredictABEL
Description: a package for genome-wide association analysis between
quantitative or binary traits and single-nucleotide
polymorphisms (SNPs).
Modified: pkg/GenABEL/R/polygenic_hglm.R
===================================================================
--- pkg/GenABEL/R/polygenic_hglm.R 2011-03-06 19:11:17 UTC (rev 667)
+++ pkg/GenABEL/R/polygenic_hglm.R 2011-03-06 19:12:16 UTC (rev 668)
@@ -93,4 +93,4 @@
class(out) <- "polygenic"
out
-}
\ No newline at end of file
+}
Modified: pkg/GenABEL/man/convert.snp.illumina.Rd
===================================================================
--- pkg/GenABEL/man/convert.snp.illumina.Rd 2011-03-06 19:11:17 UTC (rev 667)
+++ pkg/GenABEL/man/convert.snp.illumina.Rd 2011-03-06 19:12:16 UTC (rev 668)
@@ -9,7 +9,7 @@
}
\arguments{
\item{infile}{
- Pre-makeped linkage genotypic data file name
+ Map + genotypic data file name
}
\item{outfile}{
Output data file
Modified: pkg/GenABEL/man/convert.snp.mach.Rd
===================================================================
--- pkg/GenABEL/man/convert.snp.mach.Rd 2011-03-06 19:11:17 UTC (rev 667)
+++ pkg/GenABEL/man/convert.snp.mach.Rd 2011-03-06 19:12:16 UTC (rev 668)
@@ -2,7 +2,8 @@
\alias{convert.snp.mach}
\title{function to convert genotypic data from MACH format to internal data format}
\description{
-Converts genotypic data from MACH format to internal genotypic data formated file
+Converts genotypic data from MACH format to internal genotypic data formated file
+(NOT recommended)
}
\usage{
convert.snp.mach(pedfile, mapfile, infofile, outfile, quality = 0.9, column.quality = 7, strand = "+", ...)
@@ -12,7 +13,7 @@
File with genotypic data from MACH (geno or mlgeno)
}
\item{mapfile}{
- Name of the map file
+ Name of the map file (note that header line should be included)
}
\item{infofile}{
Name MACH info-file
@@ -41,6 +42,11 @@
This is a simple script converting the MACH data with \code{\link{convert.snp.ped}},
re-loading data, and filtering the snp.data object based on quality as specified in
MACH info-file
+
+ Note that it is NOT recommended to process imputations results with this procedure,
+ as uncertainty inherent to imputations is lost after processing ("hard" calls are made)!
+ For the purposes of GWA analysis, we recommend procedures, which make direct use of
+ estimated allele dose or genotypic probabilities.
}
\value{
Does not return any value, but writes file with GenABEL raw data
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