[Pomp-commits] r165 - www/content

noreply at r-forge.r-project.org noreply at r-forge.r-project.org
Tue Sep 22 23:05:54 CEST 2009


Author: kingaa
Date: 2009-09-22 23:05:54 +0200 (Tue, 22 Sep 2009)
New Revision: 165

Added:
   www/content/pomp.bib
   www/content/refs.htm
Log:
- add the references page


Added: www/content/pomp.bib
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+% This file was created with JabRef 2.5.
+% Encoding: ISO8859_1
+
+ at ARTICLE{Arulampalam2002,
+  author = {Arulampalam, M. S. and Maskell, S. and Gordon, N. and Clapp, T.},
+  title = {A Tutorial on Particle Filters for Online Nonlinear, Non-{G}aussian
+	{B}ayesian Tracking},
+  journal = {IEEE Transactions on Signal Processing},
+  year = {2002},
+  volume = {50},
+  pages = {174 -- 188},
+  doi = {10.1109/78.978374},
+  file = {Arulampalam2002.pdf:Desktop/Arulampalam2002.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2007.07.20}
+}
+
+ at ARTICLE{Breto2009,
+  author = {Carles Bret\'{o} and Daihai He and Edward L. Ionides and Aaron A.
+	King},
+  title = {Time series analysis via mechanistic models},
+  journal = {Annals of Applied Statistics},
+  year = {2009},
+  volume = {3},
+  pages = {319--348},
+  number = {1},
+  abstract = {The purpose of time series analysis via mechanistic models is to reconcile
+	the known or hypothesized structure of a dynamical system with observations
+	collected over time. We develop a framework for constructing nonlinear
+	mechanistic models and carrying out inference. Our framework permits
+	the consideration of implicit dynamic models, meaning statistical
+	models for stochastic dynamical systems which are specified by a
+	simulation algorithm to generate sample paths. Inference procedures
+	that operate on implicit models are said to have the plug-and-play
+	property. Our work builds on recently developed plug-and-play inference
+	methodology for partially observed Markov models. We introduce a
+	class of implicitly specified Markov chains with stochastic transition
+	rates, and we demonstrate its applicability to open problems in statistical
+	inference for biological systems. As one example, these models are
+	shown to give a fresh perspective on measles transmission dynamics.
+	As a second example, we present a mechanistic analysis of cholera
+	incidence data, involving interaction between two competing strains
+	of the pathogen Vibrio cholerae.},
+  doi = {10.1214/08-AOAS201},
+  file = {Breto2009.pdf:Breto2009.pdf:PDF;:Breto2009_supp.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2009.09.15}
+}
+
+ at ARTICLE{Ellner1998,
+  author = {S. P. Ellner and B. A. Bailey and G. V. Bobashev and A. R. Gallant
+	and B. T. Grenfell and D. W. Nychka},
+  title = {Noise and nonlinearity in measles epidemics: Combining mechanistic
+	and statistical approaches to population modeling},
+  journal = {American Naturalist},
+  year = {1998},
+  volume = {151},
+  pages = {425--440},
+  abstract = {We present and evaluate an approach to analyzing population dynamics
+	data using semimechanistic models. These models incorporate reliable
+	information on population structure and underlying dynamic mechanisms
+	but use nonparametric surface-fitting methods to avoid unsupported
+	assumptions about the precise form of rate equations. Using historical
+	data on measles epidemics as a case study, we show how this approach
+	can lead to better forecasts, better characterizations of the dynamics,
+	and a better understanding of the factors causing complex population
+	dynamics relative to either mechanistic models or purely descriptive
+	statistical time-series models. The semimechanistic models are found
+	to have better forecasting accuracy than either of the model types
+	used in previous analyses when tested on data not used to fit the
+	models. The dynamics are characterized as being both nonlinear and
+	noisy, and the global dynamics are clustered very tightly near the
+	border of stability (dominant Lyapunov exponent lambda approximate
+	to 0). However, locally in state space the dynamics oscillate between
+	strong short-term stability and strong short-term chaos (i.e., between
+	negative and positive local Lyapunov exponents). There is statistically
+	significant evidence for short-term chaos in all data sets examined.
+	Thus the nonlinearity in these systems is characterized by the variance
+	over state space in local measures of chaos versus stability rather
+	than a single summary measure of the overall dynamics as either chaotic
+	or nonchaotic.},
+  file = {Ellner1998.pdf:Ellner1998.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2009.09.22}
+}
+
+ at ARTICLE{He2009,
+  author = {He, Daihai and Ionides, Edward L. and King, Aaron A.},
+  title = {Plug-and-play inference for disease dynamics: measles in large and
+	small populations as a case study},
+  journal = {Journal of The Royal Society Interface},
+  year = {2009},
+  pages = {in press},
+  month = jun,
+  abstract = {Statistical inference for mechanistic models of partially observed
+	dynamic systems is an active area of research. Most existing inference
+	methods place substantial restrictions upon the form of models that
+	can be fitted and hence upon the nature of the scientific hypotheses
+	that can be entertained and the data that can be used to evaluate
+	them. In contrast, the so-called methods require only simulations
+	from a model and are thus free of such restrictions. We show the
+	utility of the plug-and-play approach in the context of an investigation
+	of measles transmission dynamics. Our novel methodology enables us
+	to ask and answer questions that previous analyses have been unable
+	to address. Specifically, we demonstrate that plug-and-play methods
+	permit the development of a modelling and inference framework applicable
+	to data from both large and small populations. We thereby obtain
+	novel insights into the nature of heterogeneity in mixing and comment
+	on the importance of including extra-demographic stochasticity as
+	a means of dealing with environmental stochasticity and model misspecification.
+	Our approach is readily applicable to many other epidemiological
+	and ecological systems.},
+  doi = {10.1098/rsif.2009.0151},
+  file = {He2009.pdf:He2009.pdf:PDF;He2009_Supplement.pdf:He2009_Supplement.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2009.06.26}
+}
+
+ at ARTICLE{Ionides2006,
+  author = {E. L. Ionides and C. Bret{\'o} and Aaron A. King},
+  title = {Inference for nonlinear dynamical systems},
+  journal = {Proceedings of the National Academy of Sciences of the United States
+	of America},
+  year = {2006},
+  volume = {103},
+  pages = {18438--18443},
+  number = {49},
+  abstract = {Nonlinear stochastic dynamical systems are widely used to model systems
+	across the sciences and engineering. Such models are natural to formulate
+	and can be analyzed mathematically and numerically. However, difficulties
+	associated with inference from time-series data about unknown parameters
+	in these models have been a constraint on their application. We present
+	a new method that makes maximum likelihood estimation feasible for
+	partially-observed nonlinear stochastic dynamical systems (also known
+	as state-space models) where this was not previously the case. The
+	method is based on a sequence of filtering operations which are shown
+	to converge to a maximum likelihood parameter estimate. We make use
+	of recent advances in nonlinear filtering in the implementation of
+	the algorithm. We apply the method to the study of cholera in Bangladesh.
+	We construct confidence intervals, perform residual analysis, and
+	apply other diagnostics. Our analysis, based upon a model capturing
+	the intrinsic nonlinear dynamics of the system, reveals some effects
+	overlooked by previous studies.},
+  doi = {10.1073/pnas.0603181103},
+  file = {Ionides2006.pdf:Ionides2006.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2006.10.06}
+}
+
+ at ARTICLE{Kendall1999,
+  author = {B. E. Kendall and C. J. Briggs and W. W. Murdoch and P. Turchin and
+	S. P. Ellner and E. McCauley and R. M. Nisbet and S. N. Wood},
+  title = {Why do populations cycle? A synthesis of statistical and mechanistic
+	modeling approaches},
+  journal = {Ecology},
+  year = {1999},
+  volume = {80},
+  pages = {1789--1805},
+  abstract = {Population cycles have long fascinated ecologists. Even in the most-studied
+	populations, however, scientists continue to dispute the relative
+	importance of various potential causes of the cycles, Over the past
+	three decades, theoretical ecologists have cataloged a large number
+	of mechanisms that are capable of generating cycles in population
+	models. At the same time, statisticians have developed new techniques
+	both for characterizing time series and for fitting population models
+	to time-series data. Both disciplines are now sufficiently advanced
+	that great gains in understanding can be made by synthesizing these
+	complementary, and heretofore mostly independent, quantitative approaches.
+	In this paper we demonstrate how to apply this synthesis to the problem
+	of population cycles, using both long-term population time series
+	and the often-rich observational and experimental data on the ecology
+	of the species in question. We quantify hypotheses by writing mathematical
+	models that embody the interactions and forces that might cause cycles.
+	Some hypotheses can be rejected out of hand, as being unable to generate
+	even qualitatively appropriate dynamics, We finish quantifying the
+	remaining hypotheses by estimating parameters, both from independent
+	experiments and from fitting the models to the time-series data using
+	modern statistical techniques, Finally, we compare simulated time
+	series generated by the models to the observed time series, using
+	a variety of statistical descriptors, which we refer to collectively
+	as "probes." The model most similar to the data, as measured by these
+	probes, is considered to be the most likely candidate to represent
+	the mechanism underlying the population cycles. We illustrate this
+	approach by analyzing one of Nicholson's blowfly populations, in
+	which we know the "true" governing mechanism. Our analysis, which
+	uses only a subset of the information available about the population,
+	uncovers the correct answer, suggesting that this synthetic approach
+	might be successfully applied to field populations as well.},
+  file = {Kendall1999.pdf:Kendall1999.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2009.09.22}
+}
+
+ at ARTICLE{Kendall2005,
+  author = {Kendall, B. E. and Ellner, S. P. and McCauley, E. and Wood, S. N.
+	and Briggs, C. J. and Murdoch, W. M. and Turchin, P.},
+  title = {Population cycles in the pine looper moth: Dynamical tests of mechanistic
+	hypotheses},
+  journal = {Ecological Monographs},
+  year = {2005},
+  volume = {75},
+  pages = {259--276},
+  number = {2},
+  abstract = {The forest insect pest Bupalus piniarius (pine looper moth) is a classic
+	example of a natural population cycle. As is typical for Populations
+	that exhibit regular oscillations in density, there are several biological
+	mechanisms that are hypothesized to be responsible for the cycles;
+	but despite several decades of detailed study there has been no definite
+	conclusion as to which mechanism is most important. We evaluated
+	three hypotheses for which there was direct experimental evidence:
+	(1) food quality (nutritional value of pine needles affected by defoliation);
+	(2) parasitoids (trophic interactions with specialist parasitoids),
+	and (3) maternal effects (maternal body size affects the performance
+	of offspring). We reviewed the empirical evidence for each of these
+	hypotheses and expressed each hypothesis in the form of a mechanistic
+	dynamic model. We used a nonlinear forecasting approach to fit each
+	model to three long-term Population time series in Britain that exhibit
+	some degree of regular cycling, and we used parametric bootstrap
+	to evaluate the significance of differences between models in their
+	goodness of fit to the data. The results differed among the three
+	forests: at Culbin, the parasitoid and maternal effects models fit
+	equally well; at Roseisle, the food quality and maternal effects
+	models fit equally well; and at Tentsmuir, the parasitoid model fit
+	best. However, the best-fit parasitism models required that the parasitism
+	rate vary between nearly 0 and nearly 1 during a cycle, greatly exceeding
+	the range of parasitism rates that have been observed in the field.
+	In contrast, the required variation in the observable maternal quality
+	variable (pupal mass) was within the range of empirical observations.
+	Under mild constraints on the parasitism rate (though allowing a
+	much wider range than has been measured in B. piniarius at any location),
+	the fit of the parasitism model fell off dramatically. The maternal
+	effects model then had uniformly strong support, outperforming the
+	constrained parasitism model at all three sites and the food quality
+	model at two; it performed slightly better than the food quality
+	model at the remaining site. This represents the first system in
+	which the maternal effects hypothesis for population cycles has been
+	supported by both strong biological and dynamical evidence.},
+  file = {Kendall2005.pdf:Kendall2005.pdf:PDF},
+  owner = {kingaa},
+  timestamp = {2009.09.22}
+}
+
+ at ARTICLE{King2008,
+  author = {King, Aaron A. and Ionides, Edward L. and Pascual, Mercedes and Bouma,
+	Menno J.},
+  title = {Inapparent infections and cholera dynamics},
+  journal = {Nature},
+  year = {2008},
+  volume = {454},
+  pages = {877--880},
+  number = {7206},
+  month = aug,
+  abstract = {In many infectious diseases, an unknown fraction of infections produce
+	symptoms mild enough to go unrecorded, a fact that can seriously
+	compromise the interpretation of epidemiological records. This is
+	true for cholera, a pandemic bacterial disease, where estimates of
+	the ratio of asymptomatic to symptomatic infections have ranged from
+	3 to 100. In the absence of direct evidence, understanding of fundamental
+	aspects of cholera transmission, immunology and control has been
+	based on assumptions about this ratio and about the immunological
+	consequences of inapparent infections. Here we show that a model
+	incorporating high asymptomatic ratio and rapidly waning immunity,
+	with infection both from human and environmental sources, explains
+	50 yr of mortality data from 26 districts of Bengal, the pathogen's
+	endemic home. We find that the asymptomatic ratio in cholera is far
+	higher than had been previously supposed and that the immunity derived
+	from mild infections wanes much more rapidly than earlier analyses
+	have indicated. We find, too, that the environmental reservoir (free-living
+	pathogen) is directly responsible for relatively few infections but
+	that it may be critical to the disease's endemicity. Our results
+	demonstrate that inapparent infections can hold the key to interpreting
+	the patterns of disease outbreaks. New statistical methods, which
+	allow rigorous maximum likelihood inference based on dynamical models
+	incorporating multiple sources and outcomes of infection, seasonality,
+	process noise, hidden variables and measurement error, make it possible
+	to test more precise hypotheses and obtain unexpected results. Our
+	experience suggests that the confrontation of time-series data with
+	mechanistic models is likely to revise our understanding of the ecology
+	of many infectious diseases.},
+  doi = {10.1038/nature07084},
+  file = {King2008.pdf:King2008.pdf:PDF;King2008_Supplement.pdf:King2008_Supplement.pdf:PDF},
+  owner = {kingaa},
+  publisher = {Macmillan Publishers Limited. All rights reserved},
+  timestamp = {2008.08.13}
+}
+
+ at comment{jabref-meta: selector_publisher:}
+
+ at comment{jabref-meta: selector_author:}
+
+ at comment{jabref-meta: selector_journal:}
+
+ at comment{jabref-meta: selector_keywords:}
+

Added: www/content/refs.htm
===================================================================
--- www/content/refs.htm	                        (rev 0)
+++ www/content/refs.htm	2009-09-22 21:05:54 UTC (rev 165)
@@ -0,0 +1,50 @@
+<h2><a name="SECTIONREF">Bibliography</a></h2>
+
+<dl compact>
+  <dt><a name="Arulampalam2002">M.&nbsp;S. Arulampalam, S.&nbsp;Maskell, N.&nbsp;Gordon, &amp; T.&nbsp;Clapp (2002).</a></dt>
+
+  <dd>`A tutorial on particle filters for online nonlinear, non-Gaussian Bayesian tracking.'<br>
+  <i>IEEE Transactions on Signal Processing</i> <b>50</b>:174 - 188.<br></dd>
+
+  <dt><a name="Breto2009">C.&nbsp;Bret&oacute;, D.&nbsp;He, E.&nbsp;L. Ionides, &amp; A.&nbsp;A. King (2009).</a></dt>
+
+  <dd>`Time series analysis via mechanistic models.'<br>
+  <i>Annals of Applied Statistics</i> <b>3</b>(1):319-348.<br></dd>
+
+  <dt><a name="Ellner1998">S.&nbsp;P. Ellner, B.&nbsp;A. Bailey, G.&nbsp;V. Bobashev, A.&nbsp;R. Gallant, B.&nbsp;T. Grenfell, &amp; D.&nbsp;W. Nychka (1998).</a></dt>
+
+  <dd>`Noise and nonlinearity in measles epidemics: Combining mechanistic and statistical approaches to population modeling.'<br>
+  <i>American Naturalist</i> <b>151</b>:425-440.<br></dd>
+
+  <dt><a name="He2009">D.&nbsp;He, E.&nbsp;L. Ionides, &amp; A.&nbsp;A. King (2009).</a></dt>
+
+  <dd>`Plug-and-play inference for disease dynamics: measles in large and small populations as a case study.'<br>
+  <i>Journal of The Royal Society Interface</i> p. in press.<br></dd>
+
+  <dt><a name="Ionides2006">E.&nbsp;L. Ionides, C.&nbsp;Bret&oacute;, &amp; A.&nbsp;A. King (2006).</a></dt>
+
+  <dd>`Inference for nonlinear dynamical systems.'<br>
+  <i>Proceedings of the National Academy of Sciences of the United States of America</i> <b>103</b>(49):18438-18443.<br></dd>
+
+  <dt><a name="Kendall1999">B.&nbsp;E. Kendall, C.&nbsp;J. Briggs, W.&nbsp;W. Murdoch, P.&nbsp;Turchin, S.&nbsp;P. Ellner, E.&nbsp;McCauley, R.&nbsp;M. Nisbet, &amp; S.&nbsp;N. Wood (1999).</a></dt>
+
+  <dd>`Why do populations cycle? a synthesis of statistical and mechanistic modeling approaches.'<br>
+  <i>Ecology</i> <b>80</b>:1789-1805.<br></dd>
+
+  <dt><a name="Kendall2005">B.&nbsp;E. Kendall, S.&nbsp;P. Ellner, E.&nbsp;McCauley, S.&nbsp;N. Wood, C.&nbsp;J. Briggs, W.&nbsp;M. Murdoch, &amp; P.&nbsp;Turchin (2005).</a></dt>
+
+  <dd>`Population cycles in the pine looper moth: Dynamical tests of mechanistic hypotheses.'<br>
+  <i>Ecological Monographs</i> <b>75</b>(2):259-276.<br></dd>
+
+  <dt><a name="King2008">A.&nbsp;A. King, E.&nbsp;L. Ionides, M.&nbsp;Pascual, &amp; M.&nbsp;J. Bouma (2008).</a></dt>
+
+  <dd>`Inapparent infections and cholera dynamics.'<br>
+  <i>Nature</i> <b>454</b>(7206):877-880.<br></dd>
+</dl>
+
+<p><br></p>
+<hr>
+
+<address>
+  Aaron A. King 2009-09-22
+</address>



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