<p class="MsoNormal">Dear All,</p><p class="MsoNormal"><br></p><p class="MsoNormal">I am using the mediation package on my research. The outcome is dichotomous and the treatment is continuous. It was run with GAM model. But I am confused with the following results. It shows all the Mediation Effect_0, Mediation Effect_1,and Mediation Effect (Average) have significant mediation effect based on 95% CI. However, the Proportion of Total Effect via Mediation_0, Proportion of Total Effect via Mediation_1, and Proportion of Total Effect via Mediation (Average) indicate there is no mediation at all based on the 95% confidence interval. The result is: </p>
<p class="MsoNormal"><br></p><p class="MsoNormal">Mediation Effect_0:<span> <font color="#000099">
</font></span><font color="#000099">-0.004309 95 % CI<span> </span>-0.0086640
-0.0007235 </font></p>
<p class="MsoNormal">Mediation Effect_1:<span>
</span><font color="#000099">-0.006557 95 % CI<span> </span>-0.014173
-0.001015 </font></p>
<p class="MsoNormal">Direct Effect_0:<span>
</span>0.04452 95 % CI<span> </span>0.001001 0.112969
</p>
<p class="MsoNormal">Direct Effect_1:<span>
</span>0.04228 95 % CI<span> </span>0.0009312
0.1061973 </p>
<p class="MsoNormal">Total Effect:<span> </span>0.03797
95 % CI<span> </span>-0.004335<span> </span>0.101359 </p>
<p class="MsoNormal">Proportion of Total Effect via Mediation_0:<span> <font color="#ff0000"> </font></span><font color="#ff0000">-0.1069 95 % CI -1.592
0.817 </font></p>
<p class="MsoNormal">Proportion of Total Effect via Mediation_1:<span> <font color="#cc0000"> </font></span><font color="#cc0000">-0.1701 95 % CI<span> </span>-1.8595<span>
</span>0.8059 </font></p>
<p class="MsoNormal">Mediation Effect (Average):<span>
</span><font color="#000099">-0.005433 95 % CI<span> </span>-0.011059
-0.000928 </font></p>
<p class="MsoNormal">Direct Effect (Average):<span>
</span>0.0434 95 % CI<span> </span>0.0009659
0.1098405 </p>
<p class="MsoNormal">Proportion of Total Effect via Mediation (Average):<span> </span><font color="#990000">-0.1391 95 % CI -1.7258
0.8114 </font></p><p class="MsoNormal"><font color="#990000"><br></font></p><p class="MsoNormal"><font color="#990000"><span class="Apple-style-span" style="color: rgb(0, 0, 0); ">Can somebody help me to explain this?</span></font></p>
<p class="MsoNormal"><font color="#990000"><span class="Apple-style-span" style="color: rgb(0, 0, 0); "><br></span></font></p><p class="MsoNormal">Thanks a lot.</p><p class="MsoNormal">Sincerely,</p><p class="MsoNormal"><br>
</p><p class="MsoNormal">Weichao</p><p class="MsoNormal"><font color="#990000"><br></font></p>