<html><head><meta http-equiv="Content-Type" content="text/html charset=windows-1252"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;">Hi,<div><br></div><div>I suggest to change the default weight argument in the GenABEL/ibs() function to be set to “freq” instead of “no”. I have colleagues constantly forget to set to “freq” and produce, what I would call, “wrong” kinship matrix.</div><div>
<br><div apple-content-edited="true">
<div style="color: rgb(0, 0, 0); font-family: Monaco; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px;  orphans: 2; widows: 2;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="font-family: Monaco; "><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="margin: 0px; font-size: 10px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="margin: 0px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="margin: 0px; font-size: 10px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="margin: 0px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="margin: 0px; font-size: 10px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="margin: 0px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-size: 9px; font-family: Arial;"><div style="margin: 0px; font-size: 10px;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="font-family: Monaco;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px;"><div style="margin: 0px; font-family: Arial;"><div style="margin: 0px;"><div style="margin: 0px;"><span style="letter-spacing: 0px;"><b>Xia Shen</b></span></div><div style="margin: 0px;"><span style="letter-spacing: 0px;">PhD</span></div><div style="margin: 0px; min-height: 11px;"><span style="letter-spacing: 0px;"></span><br></div><div style="margin: 0px;"><span style="letter-spacing: 0px;">Division of Computational Genetics</span></div><div style="margin: 0px;"><span style="letter-spacing: 0px;">Department of Clinical Science</span></div><div style="margin: 0px;"><span style="letter-spacing: 0px;"><b>Swedish University of Agricultural Sciences</b></span></div><div style="margin: 0px;"><span style="letter-spacing: 0px;">Uppsala, Sweden</span></div><div style="margin: 0px; color: rgb(2, 30, 170); min-height: 11px;"><span style="letter-spacing: 0px;"></span><br></div><div style="margin: 0px;"><span style="text-decoration: underline; letter-spacing: 0px;"><a href="http://www.shen.se">www.shen.se</a></span></div></div><div style="margin: 0px; min-height: 11px;"><span style="letter-spacing: 0px;"></span><br></div><div style="margin: 0px;"><br></div></div></span></span></span></span></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></span></span></span></span></div></div></div></span></span></span></span></div></div></span></span></span></span></div></div>
<br></div></body></html>