Thanks for comments Lennart!<div><br></div><div>I am going to add</div><div><br></div><div><div>In this talk, I will describe the \pkg{GenABEL} project in general</div><div>and will also introduce some of the packages of the suite. </div>
<div><br></div><div>A bit of problem being using 'in this talk' while I am not sure if I am getting a poster :)</div><div><br></div><div>Yurii</div><br><div class="gmail_quote">On Thu, Mar 28, 2013 at 9:21 AM, L.C. Karssen <span dir="ltr"><<a href="mailto:lennart@karssen.org" target="_blank">lennart@karssen.org</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">Hi Yurii,<br>
<br>
Looks good! The only thing I'm missing is a sentence that explains what<br>
you are going to show. Something along the lines of "I will show results<br>
obtained with GenABEL/show how to analyse a dataset using<br>
GenABEL/introduce each of the packages in the suite/...".<br>
<br>
<br>
Good luck in Spain!<br>
<br>
Lennart.<br>
<div><div class="h5"><br>
<br>
On 27/03/13 16:58, Yurii Aulchenko wrote:<br>
> Dear All,<br>
><br>
> Please find below an abstract I am going to send for the UseR! 2013<br>
> meeting.<br>
><br>
> Comments and suggestions are welcome! - the deadline is March 31<br>
><br>
> Yurii<br>
><br>
> \title{The GenABEL suite for genome-wide association analyses}<br>
><br>
> \begin{center}<br>
> {\bf Yurii S Aulchenko$^{1,2,3,^\star}$, on behalf of the GenABEL project}<br>
> \end{center}<br>
><br>
> \keywords genome-wide association scans, SNP, complex traits,<br>
> statistical genomics<br>
><br>
> \vskip 0.8cm<br>
><br>
> Genome-wide association (GWA) analysis is a widely recognized<br>
> technique for identification of genomic regions<br>
> (loci) in which changes in DNA sequence lead to changes in complex<br>
> phenotype. In GWA scans, genomes of thousands of individuals are<br>
> assessed by use of single nucleotide polymorphisms (SNP) arrays or<br>
> whole-genome resequencing to gather information on hundreds of<br>
> thousands to millions of genetic variants. The trait values of<br>
> genotyped individuals are then tested for association with this<br>
> genetic variation. During last eight years, hundreds of loci for dozens of<br>
> human common disease and other complex traits were identified using<br>
> GWA scans.<br>
><br>
> The \pkg{GenABEL} project aims to provide a free framework for<br>
> collaborative, robust, transparent, open-source based development of<br>
> statistical genomics methodology.<br>
> In the framework of this project we have developed a suite of<br>
> packages facilitating different semi-independent types of GWA analyses.<br>
> The suite currently includes nine packages, of which seven are<br>
> \proglang{R} libraries, such as the<br>
> \pkg{GenABEL} for generic GWA quality control and analyzes,<br>
> \pkg{MetABEL} for meta-analysis,<br>
> \pkg{DatABEL} for large data sets management, \pkg{VariABEL} for<br>
> identification of potentially interacting variants, and others. The packages<br>
> are distributed under GPL or LGPL and are available at the<br>
> \pkg{GenABEL} project home page, \url{<a href="http://www.genabel.org" target="_blank">http://www.genabel.org</a>}.<br>
><br>
><br>
><br>
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><br>
<span class="HOEnZb"><font color="#888888"><br>
--<br>
-----------------------------------------------------------------<br>
L.C. Karssen<br>
Utrecht<br>
The Netherlands<br>
<br>
<a href="mailto:lennart@karssen.org">lennart@karssen.org</a><br>
<a href="http://blog.karssen.org" target="_blank">http://blog.karssen.org</a><br>
<br>
Stuur mij aub geen Word of Powerpoint bestanden!<br>
Zie <a href="http://www.gnu.org/philosophy/no-word-attachments.nl.html" target="_blank">http://www.gnu.org/philosophy/no-word-attachments.nl.html</a><br>
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<div><br></div>-- <br>-----------------------------------------------------<br>Yurii S. Aulchenko<br><div><br></div><div>[ <a href="http://nl.linkedin.com/in/yuriiaulchenko" target="_blank">LinkedIn</a> ] [ <a href="http://twitter.com/YuriiAulchenko" target="_blank">Twitter</a> ] [ <a href="http://yurii-aulchenko.blogspot.nl/" target="_blank">Blog</a> ]</div>
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