<html><head><meta http-equiv="Content-Type" content="text/html charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class="">Dear Dries,<div class=""><br class=""></div><div class=""> Sorry for the late reply. This is certainly an issue we have not yet addressed with the package. Alternatively, you could produce a plot by extracting the information from the coefficients table in the BaSTA output. Here’s an option based on your results:</div><div class=""><br class=""></div><div class=""><div class=""><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: rgb(79, 79, 79);" class=""># Define the Weibull mortality with proportional hazards as:</span></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: #000000" class="">mort </span><- <span style="color: #c38809" class="">function</span>(<span style="color: #000000" class="">x</span>, <span style="color: #000000" class="">z</span>,<span style="color: #000000" class=""> b</span>,<span style="color: #000000" class=""> g</span>) {</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span class="Apple-tab-span" style="white-space:pre"> </span>exp(<span style="color: #000000" class="">g </span>* <span style="color: #000000" class="">z</span>) * (<span style="color: #000000" class="">b</span>[<span style="color: #045218" class="">1</span>] + <span style="color: #000000" class="">b</span>[<span style="color: #045218" class="">2</span>] * <span style="color: #000000" class="">b</span>[<span style="color: #045218" class="">3</span>]^(<span style="color: #000000" class="">b</span>[<span style="color: #045218" class="">2</span>]) * <span style="color: #000000" class="">x</span>^(<span style="color: #000000" class="">b</span>[<span style="color: #045218" class="">2</span>] - <span style="color: #045218" class="">1</span>))</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class="">}</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class="">where x is age, z is the SMI value, b is the vector of mortality parameters and g is the vector of proportional hazards parameters.</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153); min-height: 20px;" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79);" class=""># Define x (I’m making up this range of ages…):</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: #000000" class="">x </span><- seq(<span style="color: #045218" class="">0.1</span>, <span style="color: #045218" class="">5</span>,<span style="color: #045218" class=""> 0.1</span>)</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153); min-height: 20px;" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79);" class=""># Define the lower and upper bounds of z (these are also made up…):</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: #000000" class="">z </span><- c(<span style="color: #045218" class="">3</span>,<span style="color: #045218" class=""> 6</span>)</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153); min-height: 20px;" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79);" class=""># Extract the b and g parameters:</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco;" class="">b <span style="color: #061a99" class=""><- </span>out<span style="color: #061a99" class="">$</span>coefficients<span style="color: #061a99" class="">[</span><span style="color: #045218" class="">1</span><span style="color: #061a99" class="">:</span><span style="color: #045218" class="">3</span><span style="color: #061a99" class="">, </span><span style="color: #045218" class="">1</span><span style="color: #061a99" class="">]</span></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco;" class="">g<span style="color: #061a99" class=""> <- </span>out<span style="color: #061a99" class="">$</span>coefficients<span style="color: #061a99" class="">[</span><span style="color: #045218" class="">4</span><span style="color: #061a99" class="">, </span><span style="color: #045218" class="">1</span><span style="color: #061a99" class="">]</span></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153); min-height: 20px;" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79);" class=""># Calculate the corresponding mortalities:</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: #000000" class="">mulow </span><- mort(<span style="color: #000000" class="">x</span>,<span style="color: #000000" class=""> z</span>[<span style="color: #045218" class="">1</span>], <span style="color: #000000" class="">b</span>,<span style="color: #000000" class=""> g</span>)</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: #000000" class="">muup </span><- mort(<span style="color: #000000" class="">x</span>,<span style="color: #000000" class=""> z</span>[<span style="color: #045218" class="">2</span>], <span style="color: #000000" class="">b</span>, <span style="color: #000000" class="">g</span>)</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79); min-height: 20px;" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79);" class=""># Define the range for the y-axis:</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class=""><span style="color: #000000" class="">ylim </span><- c(<span style="color: #045218" class="">0</span>,<span style="color: #045218" class=""> </span>max(c(<span style="color: #000000" class="">mulow</span>,<span style="color: #000000" class=""> muup</span>)))</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79); min-height: 20px;" class=""><br class=""></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(79, 79, 79);" class=""># Plot the results:</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco;" class=""><span style="color: #061a99" class="">plot(</span>x<span style="color: #061a99" class="">,</span> mulow<span style="color: #061a99" class="">,</span> col <span style="color: #061a99" class="">=</span> <span style="color: #045218" class="">1</span><span style="color: #061a99" class="">,</span><span style="color: #045218" class=""> </span>type <span style="color: #061a99" class="">= </span><span style="color: #b01600" class="">'l'</span><span style="color: #061a99" class="">,</span><span style="color: #b01600" class=""> </span>ylim <span style="color: #061a99" class="">=</span> ylim<span style="color: #061a99" class="">)</span></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(6, 26, 153);" class="">lines(<span style="color: #000000" class="">x</span>,<span style="color: #000000" class=""> muup</span>, <span style="color: #000000" class="">col </span>=<span style="color: #000000" class=""> </span><span style="color: #045218" class="">2</span>)</div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco; color: rgb(176, 22, 0);" class=""><span style="color: #061a99" class="">legend(</span>'topright'<span style="color: #061a99" class="">,</span> <span style="color: #061a99" class="">c(</span>"Low SMI"<span style="color: #061a99" class="">, </span>"High SMI"<span style="color: #061a99" class="">), </span><span style="color: #000000" class="">col </span><span style="color: #061a99" class="">= c(</span><span style="color: #045218" class="">1</span><span style="color: #061a99" class="">,</span><span style="color: #045218" class=""> 2</span><span style="color: #061a99" class="">),</span></div><div style="margin: 0px 0px 0px 4px; text-indent: -4px; font-size: 15.1px; font-family: Monaco;" class=""><span style="color: #061a99" class=""><span class="Apple-tab-span" style="white-space:pre"> </span></span>lwd <span style="color: #061a99" class="">=</span> <span style="color: #045218" class="">2</span><span style="color: #061a99" class="">)</span></div></div><div class=""><br class=""></div><div class=""> Let me know if this is of any help.</div><div class="">
<div style="color: rgb(0, 0, 0); font-family: Helvetica; font-size: 16px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; orphans: 2; widows: 2;" class=""><br class="Apple-interchange-newline">Best,</div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-size: 16px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; orphans: 2; widows: 2;" class=""><br class=""></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-size: 16px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; orphans: 2; widows: 2;" class="">Fernando<br class="Apple-interchange-newline"><br class=""></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class=""><b class="">Fernando Colchero</b></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Assistant Professor</div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Department of Mathematics and Computer Science</div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Max-Planck Odense Center on the Biodemography of Aging</div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class=""><b class=""><i class=""><br class=""></i></b></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Tlf. +45 65 50 23 24</div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Email <a href="mailto:colchero@imada.sdu.dk" class="">colchero@imada.sdu.dk</a></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Web <a href="http://www.sdu.dk/staff/colchero" class="">www.sdu.dk/staff/colchero</a></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Pers. web <a href="http://www.sdu.dk/staff/colchero" class="">www.colchero.com</a></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class="">Adr. Campusvej 55, 5230, Odense, Dk</div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class=""><br class=""></div><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; font-size: 12px; orphans: 2; widows: 2;" class=""><b class="">University of Southern Denmark</b></div>
</div>
<br class=""><div><blockquote type="cite" class=""><div class="">On 22 Mar 2016, at 11:32, Dries Van de Loock <<a href="mailto:dries.vandeloock@ugent.be" class="">dries.vandeloock@ugent.be</a>> wrote:</div><br class="Apple-interchange-newline"><div class=""><meta http-equiv="Content-Type" content="text/html; charset=utf-8" class=""><div dir="ltr" class=""><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Dear BaSTA community, </span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Thanks to your help and BaSTA, we could
statistically confirm some of our expectations on <a href="http://lists.r-forge.r-project.org/pipermail/basta-users/2015-October/000131.html" class="">post-fledging survival in a afrotropical passerine</a>. </span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">While <i class="">plotfancybasta()</i> and <i class="">plot() </i>produce
nice graphs for categorical variables, we are looking for a way to visualise the
impact of <b class="">continues covariates</b> on survival of the fledglings. </span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">More specifically, we fitted a
weibull survival curve with makeham shape + mass at fledging (SMI) as a
covariate (base model + 1 covariate) and find a negative relation with
mortality (CI does not include zero). </span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class="">Coefficients:</span></pre><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class=""> Estimate StdErr Lower95%CI Upper95%CI SerAutocor UpdateRate PotScaleReduc</span></pre><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class="">c 0.02704 0.01595 0.009527 0.066033 0.56051 0.2223 1.017</span></pre><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class="">b0 0.06541 0.06751 0.001576 0.252938 0.38508 0.2605 1.002</span></pre><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class="">b1 0.90422 0.63824 0.043231 2.358846 0.06547 0.2501 1.001</span></pre><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class=""><span style="background-color:rgb(255,255,0)" class="">gamma.SMI -0.03971 0.01978 -0.083632 -0.006801</span> 0.55284 0.2526 1.003</span></pre><pre style="line-height:10.25pt;background-image:initial;background-repeat:initial" class=""><span lang="EN-GB" style="font-size: 8pt; font-family: Courier;" class="">pi.1 0.14211 0.01089 0.121642 0.163994 0.03578 1.0000 1.001</span></pre><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">We see two ways to visualise this</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class=""><br class=""></span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">1. Daily mortality rates over a two
month period (y-axis) plotted against time (x-axis) for a discrete number of
SMI values. As such, you visualise the mortality shape for a number of SMI
values over a two month period. </span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class=""><br class=""></span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">2. The cumulative mortality probabilities
(y-axis) after a two month period plotted against SMI (x-axis). We then expect
that cumulative mortality probabilities will decrease with increasing SMI.</span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">To do this, we could use the
estimates to calculate (i) the daily mortality rates over a two month period
and use these to calculate (ii) the cumulative mortality probabilities after a
two month period for a discrete number of SMI values within the measured range (for
example : 20, 25,30,35). </span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class=""><br class=""></span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">While we successfully calculate
daily mortality rates fitting the estimates in the function (b0 * b1 * ((b1 *
k)^(b0 - 1))) + c) when no covariates were added to the model, we failed to
find a method on how to include the gamma estimate in the function. </span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class=""><br class=""></span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Any help on how we can calculate
daily mortality rates for a specific value of the covariate and be able to
produce these graphs is highly appreciated. </span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Best wishes, </span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Dries Van de Loock</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">PhD student</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Terrestrial Ecology Unit</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Department of Biology</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Ghent University</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">KL Ledeganckstraat 35</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">B-9000 Ghent, Belgium</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class="">Phone: +32 (0)9 265 50 39</span></p><p class="MsoNormal" style="margin-bottom:0.0001pt"><span lang="EN-GB" class=""><a href="http://www.ecology.ugent.be/terec/" class="">http://www.ecology.ugent.be/terec/</a></span></p><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div><div style="margin-bottom: 0.0001pt;" class="">
<br class="webkit-block-placeholder"></div><div style="margin-bottom: 0.0001pt;" class=""><span lang="EN-GB" class=""> </span><br class="webkit-block-placeholder"></div></div>
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